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Here we set out to evaluate the roles
2018-10-31
Here we set out to evaluate the roles of transcriptional regulators associated with EMT in iPSC reprogramming. We were intrigued by data from published reports that EMT factors (including SNAI1) increased during the early stages of reprogramming (Mikkelsen et al., 2008; Samavarchi-Tehrani et al., 20
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RGDfK Although the disease specific phenotype identified
2018-10-31
Although the disease specific phenotype identified in this study will be invaluable for demonstrating the efficacy of gene based therapeutics, two major questions remain: 1) why do some patients with TRNT1 variants develop the severe syndromic disease SIFD while others (i.e. the three presented in t
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Compared to treatments with other FGF isoforms stimulation
2018-10-31
Compared to treatments with other FGF2 isoforms, stimulation with 22.5kDa FGF2 results in lower stem cell gene expression in hESCs (Fig. 4d), weaker proliferative activity in human dermal fibroblasts (Fig. 5), and lower relative mitogenic activity in BaF3 casr ectopically expressing FGFR1 IIIb, one
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To obtain source cells for reprogramming in isogenic setting
2018-10-31
To obtain source GSK503 cost for reprogramming in isogenic settings (Figure 1A), we isolated equine MABs in isogenic settings with MSC lines, which were already established from peripheral blood (Spaas et al., 2013), and demonstrated chondrogenic commitment (Broeckx et al., 2014). We adapted the pro
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renin inhibitor br The corresponding number of trajectories
2018-10-30
The corresponding number of trajectories is ten at h=3d= 1.2mm, and the ‘useful’ area increases: After choosing relative position of the emitter and lens end, calculations were done of how to transport and focus the beam by the lens. It was again implemented with the use of the program ‘Simion7
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Migration itself may be considered a transition along the
2018-10-30
Migration itself may be considered a transition along the individual life-course. For example, transketolase from historic ‘sending’ communities (e.g. Western Mexico) may be considered a normative transition for young adults, as part of an expected trajectory of life and work in the U.S. (Massey, A
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Analysts may empirically check if the outcome variable has a
2018-10-30
Analysts may empirically check if the outcome variable has an ICC that tyrosine kinase receptor is distinguishable from zero, as introduced briefly above. Even those favoring a priori specification of how the model will account for clustering, coauthor or reviewer suggestions may warrant an empiric
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We are particularly interested in how socioeconomic status S
2018-10-30
We are particularly interested in how socioeconomic status (SES) is associated with multimorbidity earlier in the lifecourse. Low SES has been linked to greater occurrence of numerous individual chronic conditions, including hypertension (Vargas, Ingram, & Gillum, 2000) heart disease (Thurston, Kubz
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The analysis of age specific
2018-10-30
The analysis of age-specific recommended sleep durations revealed similar results: the significantly highest proportion of patients with non-recommended low sleep duration (43%) was found among patients with SUD (AND 24%; SCZ 10%; c.f. Table 2). No significant gender differences were found with res
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To establish the sensor s specificity and reproducibility fo
2018-10-30
To establish the sensor’s specificity and reproducibility for Hg2+ detection in the field, the response to other potential contaminants must be minimized. The sensor was tested with a variety of other ions, including common environmental contaminants, e.g., Na+, Fe3+, Ca2+, Pb2+, and Cd2+ with the s
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When the capacitor was connected to the Al phosphate cell
2018-10-30
When the capacitor was connected to the Al/phosphate cell via a switch capacitor regulator circuit and was charged from 1.4V to 1.8V, the charging times were 0.51±0.02s and 0.34±0.03s for the single cell and the 2-cell configuration, respectively (Fig. 5). The charge/discharge cycle was observed app
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mandato constitucional al Banco de M xico
2018-10-30
mandato constitucional al Banco de México es procurar la estabilidad del poder adquisitivo de la moneda nacional. El Decreto establece que la Secretaría de Hacienda y Crédito Público () constituirá un fideicomiso en dicho Banco, apoptosis research fin de recibir, administrar y distribuir los ingres
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br Experimental br Results and
2018-10-30
Experimental Results and discussion Conclusion A proof of concept direct conversion solid-state leptomycin b dosimeter was fabricated by combining the large neutron capture cross-section of 10B with the charge trapping attributes of double layer sub-2nm Pt nanoparticles (Pt NPs) in scalable
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El a o de la
2018-10-30
El año de la crisis, las exportaciones reaccionaron claramente ante la devaluación cambiaria y, junto con un entorno económico internacional positivo, las petroleras y las no petroleras se expandieron. Este aumento compensó, parcialmente, la caída del gasto interno. Pero ese año, el crecimiento econ
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La experimentaci n por asignaci n
2018-10-30
La experimentación por asignación aleatoria es una técnica proveniente de las ciencias de la salud e “importada” desde hace aproximadamente quince años al campo de las políticas públicas y de la Economía del Desarrollo. Esta transferencia se opera en el doble contexto de debilitamiento del Consenso
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