• Importantly expression of SMA is not simply a marker for

  2018-11-09

  

  Importantly, expression of α-SMA is not simply a marker for MF activation, but also the driver of cell function and fate. Increased expression of α-SMA directly reduces the clonal potential of hMSCs and guides their differentiation toward osteoblasts. Hence, α-SMA not only identifies osteoprogenitor

• The nuclear factor kappa B

  2018-11-09

  

  The nuclear factor kappa B (NF-κB) is known for its key role in the regulation of many cellular processes. The classical NF-κB is a heterodimer of p50 and p65/RelA proteins, in which the p65/RelA subunit has transactivation activity. The IκB kinase (IKK) complex mediates the degradation of IκBs to a

• Dedifferentiation has been considered as

  2018-11-09

  

  Dedifferentiation has been considered as one of the mechanisms rerouting cell fate by reverting differentiated cells to an earlier, more primitive phenotype. Interestingly, previous studies from both our group and others have demonstrated that dedifferentiation is a prerequisite for bone marrow stro

• The experimental data of Ref prove that

  2018-11-09

  

  The experimental data of Ref. [32] prove that the yield point is particularly strongly dependent on hydrogen concentration. A linearly elastic material may be logically assumed to have a free surface area that, for small strains, is proportional to the deformation itself. Consequently, the α and β

• br Introduction For Crocco s equation given on the

  2018-11-09

  

  Introduction For Crocco\'s equation given on the interval 0 0, f ∈ L1(0, 1), it SAR 405 is possible to set various boundary problems. First of all, a typical boundary problem can be set: Aside from this one, a boundary problem homogeneous in φ(h) can be set: as well as a combined homogeneo

• br Conclusions The exact solution

  2018-11-09

  

  Conclusions The exact solution of the Gibbs–Tolman–König–Buff equation makes it possible to describe the relationship between the melting point and the particle sizes ranging from 3 to 20nm more adequately, which goes to further prove that surface tension forces play the decisive role in the init

• The possibility of observing a new type

  2018-11-09

  

  The possibility of observing a new type of quantum transport in an inelastic channel was predicted on the assumption that the motion of electrons occurs in such a manner that in addition to inelastic scattering, the electrons experience single scattering through a large angle. Later it was revealed

• The present findings can be alternatively explained by

  2018-11-09

  

  The present findings can be alternatively explained by a progressive enhancement of the neural visual system while children learn to read. In this case, the present changes in Gefitinib responses to visual objects would be mainly due to a specific improvement of basic perceptual skills as the resul

• Results br Discussion The aim of this study was

  2018-11-09

  

  Results Discussion The aim of this study was to examine the neural correlates of facial affect processing across this sensitive period of adolescent socioemotional development by using a highly ecologically valid stimulus set and paradigm (assessing implicit regulation of dynamic adolescent expr

• Previous research has described the effects of eight

  2018-11-09

  

  Previous research has described the effects of eight-week mindfulness meditation instruction on neural connectivity (e.g., ), and Shao further extends this work. The Shao study is a note-worthy contribution, especially related to the rigorous randomized active-control study design, longitudinal appr

• A central challenge to advancing

  2018-11-09

  

  A central challenge to advancing therapy for progressive PTC is to improve the responses to tyrosine kinase receptor therapy, while minimizing toxicity. So far, the response rates are typically 20% (range 0–45%) and there was substantial toxicity documented from trials using tyrosine kinase receptor

• br Use of Adipose Stem Cells to

  2018-11-09

  

  Use of Adipose Stem Cells to Treat Inflammatory Diseases In a session dedicated to MSC Gene & Cell Therapy, Wilfried Daelemans from TiGenix (Leuven, Belgium), presented data on the use of expanded allogeneic Adipose-derived Mesenchymal Stem Cells (ASCs) to treat inflammatory disorders. The ration

• The findings are also consistent with the few prior

  2018-11-09

  

  The findings are also consistent with the few prior studies that have indexed social perception using the P400 component. The same ERP component that here indexes social valence has previously been documented to index social perception of various stimuli, including goal directed grasping (Bakker et

• Notably a recent training study asked

  2018-11-09

  

  Notably, a recent training study asked 6 years old preschoolers to learn grapheme to phoneme correspondence. Although these children had already acquired some letter knowledge (10 upper case letters and 5.8 lower case letters) prior to training, they did not possess neural tuning for words associate

• Risk behaviours are important threats during adolescence

  2018-11-09

  

  Risk behaviours are important threats during adolescence due to possible lifetime negative consequences. Their prevalence is high in the USA: the percentage of those who ever smoke, drunk, use marijuana and cocaine was respectively 44.7, 70.6, 39.9 and 18.2% in a national survey; the percentages of

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