• Rationale Anterior cervical discectomy and fusion ACDF has

  2018-10-29

  

  Rationale Anterior cervical discectomy and fusion (ACDF) has been accepted as the gold standard of surgical management for cervical spondylosis and disc disease causing radiculopathy or myelopathy. High patient-satisfaction scores and high arthrodesis rates associated with ACDF have been reported i

• br Material and methods br

  2018-10-29

  

  Material and methods Results Discussion Differentiated chondrocytes are capable of proliferating and secreting numerous growth factors and cytokines to form the extracellular matrix in mature cartilage (Fischer et al., 2010; Keller et al., 2011). During chondrogenesis, these events are prec

• br Conclusions br Materials and

  2018-10-29

  

  Conclusions Materials and methods Acknowledgments This work was supported by funds from the Alliance of Cardiovascular Researchers. We would also like to give special thanks and express our gratitude to Drs. Edward Newsome, Ernest Chiu, and David Jansen for their valuable contributions to t

• Our ChIP seq data indicate that Cdx and Sall engage

  2018-10-29

  

  Our ChIP-seq data indicate that Cdx4 and Sall4 engage in auto- and cross-regulatory loops. Such regulatory circuits are frequently seen during embryonic development. For example, during segmentation of rhombomere 4 in the mouse hindbrain, retinoic g-quadruplex signaling first turns on HoxB1, followe

• Introduction Induced pluripotent stem cells

  2018-10-26

  

  Introduction Induced pluripotent stem SW033291 (iPSC) have been used in an increasing number of applications since Takahashi and Yamanaka (Takahashi and Yamanaka, 2006) first demonstrated the reprogramming of adult somatic cells to produce iPSC. In combination with gene editing technology iPSC have

• In summary using the Nurr

  2018-10-26

  

  In summary, using the Nurr1 agonist AQ we first showed that Nurr1 plays an important role in the regulation of adult hippocampal neurogenesis. AQ may increase adult hippocampal neurogenesis via, in part, an up-regulated phosphorylation of Akt and ERK1/2. Moreover, the Nurr1 agonist enhances both sho

• br Results To investigate the molecular

  2018-10-26

  

  Results To investigate the molecular and cellular phenotypes perturbed in DS, we compared DS and normal ESCs and their neural derivatives. In the past, we have isolated three DS-ESC lines, namely CSES13, CSES20, and CSES21, from PGS-derived embryos with trisomy of chromosome 21 (Figure 1A) (Bianc

• Dedifferentiation has been considered as

  2018-10-26

  

  Dedifferentiation has been considered as one of the mechanisms rerouting cell fate by reverting differentiated cells to an earlier, more primitive phenotype. Interestingly, previous studies from both our group and others have demonstrated that dedifferentiation is a prerequisite for bone marrow stro

• In recent series of experiments at Mainzer Microtron with an

  2018-10-26

  

  In recent series of experiments at Mainzer Microtron [5] with 600 and 855 MeV electrons the effect of a small-amplitude short-period undulator was observed. Another set of experiments with diamond crystalline undulators is planned within the E-212 collaboration at the SLAC facility (Stanford Linear

• Fiber separation in the reinforcing yarns

  2018-10-26

  

  Fiber separation in the reinforcing yarns and damages in the yarn matrix may occur during the deformation of flexible woven composite materials due to debonding between the reinforcing fibers and the adhesive. These processes can be described as \'smeared cracks’ [18-21]. This description is based o

• In examining why African American patients of midwifery care

  2018-10-26

  

  In examining why African American patients of midwifery care had lower prevalence of adverse infant birth outcomes in two of these studies, it is important to assess the significance of “race”. Nancy Krieger defines race/ethnicity as “a social, not biological, category, referring to social groups, o

• It is well known that recent immigrants to the

  2018-10-26

  

  It is well known that recent immigrants to the US have the most favorable health profile (Ullmann, Goldman, & Massey, 2011), while greater duration of residence is associated with poorer health and mortality outcomes (Creighton, Goldman, Pebley, & Chung, 2012). In addition, those immigrants who arri

• br Methods br Results br Discussion

  2018-10-26

  

  Methods Results Discussion As expected, the baseline mean SBP values were substantially higher in the low-income group. Further, there were no differences in SBP means by smoking status only among the low-income group, while the mean SBP was 1.7mmHg higher in smokers vs. non-smokers in the

• Therefore given that vocal pitch is a defining characteristi

  2018-10-26

  

  Therefore, given that vocal pitch is a defining characteristic that conveys personality and distinguishes it folate analogue from others (Piñeiro Otero, 2010; Tigue, Borak, O’Connor, Schandl, & Feinberg, 2012), the question that arises when considering the common practice in radio is the following:

• Although it appears that hypercortisolemia may contribute to

  2018-10-26

  

  Although it appears that hypercortisolemia may contribute to the development of different features of metabolic syndrome, it is not clear in the literature whether glucocorticoids play a role in the pathogenesis of obesity. Some studies show that Metformin cost levels are not higher in obese subject

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